Where is South San Francisco, California, U.S.

Written and Fact-checked by | Updated On: March 05, 2026, 14:55 ET

Where is South San Francisco, California Located in the United States? - South San Francisco is a city located in the San Mateo County in California, United States. South San Francisco lies between 37.6547 Degrees North latitudes and -122.4077 Degrees West longitudes.

Location Map of South San Francisco, San Mateo, California

Where is South San Francisco Located in San Mateo, California

About Map: The map shows the location of South San Francisco in San Mateo County, in the U.S. state of California.

South San Francisco Map, California, USA

About South San Francisco Map: This Google Map provides a detailed view with zoom, satellite, and street options to explore the area and its surroundings.

About South San Francisco, San Mateo County, California

South San Francisco is located in San Mateo County in the U.S. state of California, United States. It lies in the northern part of the state in the state of the United States along the San Francisco Peninsula within the Bay Area region. The city was incorporated in 1908 and was named for its proximity to San Francisco, and it developed as an industrial center before becoming a major hub for biotechnology and research companies.

Population

According to the United States Census Bureau, the population of South San Francisco is 66,105 as recorded in the 2020 Census, and the population density is approximately 7,600 people per square mile.

Area and Geography

According to the United States Census Bureau, South San Francisco covers a total area of approximately 30.2 square miles (about 78.2 square kilometers), including about 9.1 square miles (23.6 square kilometers) of land and 21.1 square miles (54.6 square kilometers) of water.

Location and Surroundings

South San Francisco is situated south of San Bruno and north of Daly City, positioned along the western shoreline of San Francisco Bay. The city features a mix of residential neighborhoods, industrial districts, and hillside areas rising toward the Santa Cruz Mountains. U.S. Route 101 runs through the city, providing a major transportation route connecting South San Francisco to downtown San Francisco and Silicon Valley.

Attractions and Recreation

South San Francisco offers parks, cultural landmarks, and scenic viewpoints that support recreation and tourism. Popular destinations include Sign Hill Park, Orange Memorial Park, and the South San Francisco Conference Center. The city hosts community events and cultural programs that reflect its diverse population and economic role in the region.

Transportation

South San Francisco is served by U.S. Route 101 and Interstate 280, offering convenient highway access throughout the Bay Area. Public transportation includes Caltrain commuter rail service and regional bus connections linking the city to surrounding communities. The nearest major airport is San Francisco International Airport, located approximately 3 miles to the south.

Explore more cities in California or visit the United States Map section to learn more about the country’s geography.

Sources:

Population and area data sourced from the United States Census Bureau (2020 Census). General city information referenced from the Official South San Francisco City Website.

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South San Francisco City Facts

CitySouth San Francisco
StateCalifornia
CountySan Mateo County
CountryUnited States
RegionSan Francisco Bay Area - Peninsula
IncorporatedSeptember 19, 1908
Founded1894
Total AreaApproximately 30.2 sq mi (78.2 km2)
Land AreaApproximately 9.1 sq mi (23.6 km2)
Water AreaApproximately 21.1 sq mi (54.6 km2)
ElevationApproximately 20 ft (6 m)
Population (2023 estimate)Approximately 67,000+
Population (2020 Census)66,105
Population DensityApproximately 7,200 people per sq mi
Time ZonePacific Time (UTC-8 / UTC-7 DST)
ZIP Codes94080, 94083
Area Code650
Major HighwaysU.S. Route 101, Interstate 280, State Route 82
Public TransitCaltrain, SamTrans, BART (nearby)
Major AttractionsSign Hill Park, Oyster Point Marina, South San Francisco Conference Center
Official Websitehttps://www.ssf.net/

Distance from South San Francisco City, CA to Nearby Cities

  • San Bruno, CA – 3 miles (5 km)
  • Daly City, CA – 5 miles (8 km)
  • Millbrae, CA – 4 miles (6 km)
  • Burlingame, CA – 6 miles (10 km)
  • San Mateo, CA – 10 miles (16 km)
  • Pacifica, CA – 8 miles (13 km)
  • Colma, CA – 4 miles (6 km)
  • Redwood City, CA – 20 miles (32 km)
  • Foster City, CA – 12 miles (19 km)
  • Belmont, CA – 15 miles (24 km)
  • Half Moon Bay, CA – 20 miles (32 km)
  • Menlo Park, CA – 22 miles (35 km)
  • Palo Alto, CA – 25 miles (40 km)
  • Mountain View, CA – 30 miles (48 km)
  • San Francisco, CA – 10 miles (16 km)
  • Oakland, CA – 20 miles (32 km)
  • Berkeley, CA – 25 miles (40 km)
  • Hayward, CA – 25 miles (40 km)
  • Fremont, CA – 35 miles (56 km)
  • San Jose, CA – 45 miles (72 km)

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