Where is Sikeston, Missouri

Written and Fact-checked by | Updated On: August 5, 2026

Sikeston is a city in southeastern Missouri and part of the Bootheel region, with portions extending into Scott and New Madrid counties. Located about 30 miles west of Cape Girardeau, the city sits near major highways connecting St. Louis, Memphis, and the Mississippi River region. Sikeston is known for its historic downtown, agricultural roots, and nearby Southeast Missouri attractions.

Location Map of Sikeston, Scott County, Missouri

Where is Sikeston Located in Scott County, Missouri

About Map: The map shows the location of Sikeston in Scott County, in the U.S. state of Missouri.

Sikeston Map, Missouri

About Sikeston Map: The Google Map highlights the location of Sikeston in Scott County, Missouri. Use the zoom, satellite, and street-view options to explore the city's neighborhoods, roads, and nearby places.

Where is Sikeston Located?

Sikeston is a city located in Scott County, Missouri, the United States. It lies in the Missouri Bootheel near the transition between the Mississippi River lowlands and the Ozark foothills. Sikeston is about 30 miles west of Cape Girardeau, 45 miles north of New Madrid, and roughly 150 miles south of St. Louis. Memphis, Tennessee, is about 130 miles south of the city. Sikeston is located at 36.8767° North latitude and 89.5879° West longitude. The 2020 Census recorded 16,318 residents. The city covers about 17.5 square miles (45.3 square kilometers), with most of the area consisting of land. Sikeston is surrounded by productive farmland and has long served as a regional center for agriculture, transportation, and commerce. The Sikeston Depot Museum is a notable local attraction. A unique feature of Sikeston is its location at the junction of Interstate 55 and Interstate 57, making it an important transportation point between the Midwest and the South.

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Sikeston City Facts

FactDetails
CitySikeston
StateMissouri
CountyScott County
CountryUnited States
RegionMissouri Bootheel, Southeast Missouri
Incorporated1876
Founded1860
Total Area17.5 sq mi (45.3 sq km)
Land Area17.4 sq mi (45.1 sq km)
Water Area0.1 sq mi (0.2 sq km)
ElevationAbout 315 ft (96 m)
Population (2023 estimate)About 16,000
Population (2020 Census)16,318
Population DensityAbout 936 people per sq mi
Time ZoneCentral Time (CST/CDT)
ZIP Codes63801
Area Code573
Major HighwaysInterstate 55, Interstate 57, U.S. Highway 62, U.S. Highway 60
Public TransitBootheel Regional Consortium transportation services
Major AttractionsSikeston Depot Museum, Sikeston Jaycee Bootheel Rodeo, Sikeston Factory Outlet Stores, Cape Girardeau area
Official Websitehttps://www.sikeston.net/

Distance from Sikeston, MO to Nearby Cities

  • Scott City, MO – 10 miles (16 km)
  • Charleston, MO – 15 miles (24 km)
  • East Prairie, MO – 25 miles (40 km)
  • New Madrid, MO – 30 miles (48 km)
  • Cape Girardeau, MO – 30 miles (48 km)
  • Bloomfield, MO – 35 miles (56 km)
  • Dexter, MO – 35 miles (56 km)
  • Poplar Bluff, MO – 55 miles (89 km)
  • Kennett, MO – 55 miles (89 km)
  • Caruthersville, MO – 45 miles (72 km)
  • Marion, IL – 65 miles (105 km)
  • Paducah, KY – 75 miles (121 km)
  • Jonesboro, AR – 85 miles (137 km)
  • Paragould, AR – 75 miles (121 km)
  • Jackson, MO – 25 miles (40 km)
  • Farmington, MO – 100 miles (161 km)
  • St. Louis, MO – 150 miles (241 km)
  • Memphis, TN – 130 miles (209 km)

Top Attractions in Sikeston, Missouri

  • Sikeston Depot Museum – A local museum housed in a historic railroad depot that preserves artifacts and stories from Sikeston and the surrounding region.
  • Sikeston Jaycee Bootheel Rodeo – A major annual community event featuring rodeo competitions, livestock activities, entertainment, and regional traditions.
  • Sikeston Factory Outlet Stores – A regional shopping destination along Interstate 55 with outlet retailers and travel-oriented services.
  • Malone Park – A community recreation area with open space, walking areas, sports facilities, playgrounds, and picnic areas.
  • Front Street – A historic area in Sikeston with older commercial buildings, local businesses, and connections to the city's early development.
  • Bootheel Golf Club – A local golf facility offering a course and recreational opportunities in the Sikeston area.
  • Lake Wappapello State Park – A large nearby recreation area with a reservoir, forests, hiking trails, boating, fishing, and camping.
  • New Madrid Historical Museum – A regional museum preserving the history of New Madrid and the major earthquakes that affected the Mississippi Valley in the early 19th century.
  • Trail of Tears State Park – A Mississippi River park north of Cape Girardeau with hiking trails, camping, fishing, and historic interpretation.

Airports Near Sikeston, Missouri

  • Sikeston Memorial Municipal Airport (SIK) – 5 miles
  • Cape Girardeau Regional Airport (CGI) – 35 miles
  • Poplar Bluff Municipal Airport (POF) – 60 miles
  • Williamson County Regional Airport (MWA) – 70 miles

Sources:

Population and area data sourced from the United States Census Bureau (2020 Census). General city information referenced from the official Sikeston city website and local government records.

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