Where is De Soto, Missouri

Written and Fact-checked by | Updated On: August 5, 2026

De Soto, Missouri is a small city south of St. Louis in Jefferson County. It has a long railroad and mining history and is surrounded by the wooded hills of eastern Missouri. The city is about 45 miles south of St. Louis and offers easy access to parks, lakes, and outdoor areas.

Location Map of De Soto, Jefferson County, Missouri

Where is De Soto Located in Jefferson County, Missouri

About Map: The map shows the location of De Soto in Jefferson County, in the U.S. state of Missouri.

De Soto Map, Missouri

About De Soto Map: The Google Map highlights the location of De Soto in Jefferson County, Missouri. Use the zoom, satellite, and street-view options to explore the city's neighborhoods, roads, and nearby places.

Where is De Soto Located?

De Soto is a city in Jefferson County, Missouri. It is about 45 miles south of St. Louis and lies near the wooded hills of eastern Missouri.

Most Viewed US Maps

USA Sttae MapUSA Region MapUSA Road Map
USA County MapWhere is USA in World Map?US ZIP Code Map
USA Time Zones MapUS State and Capitals MapUSA Physical Map
Looking for a U.S. City?
Find 4,400+ U.S. Cities by State - Explore Their Locations and Get Detailed Information

De Soto City Facts

FactDetails
CityDe Soto
StateMissouri
CountyJefferson County
CountryUnited States
RegionEastern Missouri / St. Louis Metropolitan Area
Incorporated1857
Founded1857
Total Area5.35 sq mi (13.86 sq km)
Land Area5.30 sq mi (13.73 sq km)
Water Area0.05 sq mi (0.13 sq km)
ElevationAbout 620 ft (189 m)
Population (2023 estimate)About 6,400
Population (2020 Census)6,449
Population DensityAbout 1,217 people per sq mi
Time ZoneCentral Standard Time (CST); Central Daylight Time (CDT)
ZIP Code63020
Area Code636
Major HighwaysU.S. Route 67, Missouri Route 110, Missouri Route 21
Public TransitJefferson County public transportation services
Major AttractionsWashington State Park, St. Joe State Park, Bonne Terre Mine, De Soto Historic District
Official Websitehttps://www.desotomissouri.org/

Distance from De Soto, MO to Nearby Cities

  • Hillsboro, MO – 15 miles (24 km)
  • Festus, MO – 15 miles (24 km)
  • Crystal City, MO – 15 miles (24 km)
  • Bonne Terre, MO – 20 miles (32 km)
  • Park Hills, MO – 25 miles (40 km)
  • Desloge, MO – 30 miles (48 km)
  • Farmington, MO – 35 miles (56 km)
  • Ste. Genevieve, MO – 30 miles (48 km)
  • Arnold, MO – 30 miles (48 km)
  • Pevely, MO – 25 miles (40 km)
  • St. Louis, MO – 45 miles (72 km)
  • Washington, MO – 65 miles (105 km)
  • Columbia, MO – 120 miles (193 km)
  • Cape Girardeau, MO – 80 miles (129 km)
  • Springfield, MO – 200 miles (322 km)
  • Memphis, TN – 190 miles (306 km)
  • Kansas City, MO – 270 miles (435 km)

Top Attractions in De Soto

  • Washington State Park – Nearby park known for its historic petroglyphs, wooded trails, camping, fishing, and scenic views.
  • St. Joe State Park – Large recreation area with lakes, trails, camping, swimming, fishing, and off-road vehicle trails.
  • Bonne Terre Mine – Historic former lead mine offering tours and unique underground attractions.
  • De Soto Historic District – Area with historic buildings, local businesses, churches, and landmarks reflecting the city's railroad and mining history.
  • Jefferson County Historical Society Museum – Local museum preserving artifacts and stories from Jefferson County's past.
  • De Soto City Park – Community recreation area with green space, playgrounds, walking areas, and sports facilities.
  • Pickle Springs Natural Area – Scenic natural area with unusual sandstone rock formations, hiking trails, and forest scenery.
  • Elephant Rocks State Park – Nearby park famous for huge granite formations, hiking trails, and historic railroad features.

Airports Near De Soto

  • Farmington Regional Airport (FAM) – 35 miles
  • St. Louis Lambert International Airport (STL) – 60 miles
  • St. Louis Downtown Airport (CPS) – 45 miles
  • Spirit of St. Louis Airport (SUS) – 65 miles
  • MidAmerica St. Louis Airport (BLV) – 60 miles

Sources:

Population and area data sourced from the United States Census Bureau (2020 Census). General city information referenced from the official City of De Soto website and local government records.

Other Missouri Maps & Info

Missouri MapMissouri County MapMap of Missouri With Cities
Missouri ZipcodesAirports in MissouriWhere is St. Louis
Missouri Area CodesWhere is MissouriMissouri River Map
Missouri Physical MapMissouri Road MapWhere is Kansas City