Mississippi County Map, Missouri

Written and Fact-checked by | Last Updated: November 01, 2025, 14:20 ET

Map of Mississippi County - Mississippi County is a county located in the U.S. state of Missouri. Mississippi County Map showing cities, highways, important places and water bodies. Get Where is Mississippi County located in the map, major cities in Mississippi county, population, areas, and places of interest.

Map of Mississippi County, Missouri

Map of Mississippi County, Missouri

About Mississippi County Map, Missouri: The map showing the county boundary, county seat, major cities, highways, water bodies and neighbouring counties.

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Mississippi County, Missouri

Mississippi County is a county located in the U.S. state of Missouri. It's county seat is Charleston. As per 2020 census, the population of Mississippi County is 12538 people and population density is square miles. According to the United States Census Bureau, the county has a total area of 413 sq mi (1,070 km2). Mississippi County was established on 1842.

Mississippi County Facts

ContinentNorth America
CountryUnited States
StateMissouri
County SeatCharleston
Largest City/TownSikeston nearby region
Established1845
Total Area423 sq mi (1,096 sq km)
Land Area412 sq mi (1,067 sq km)
Water Area11 sq mi (29 sq km)
Population12,577 (Census 2020)
Population Density30.5 people per sq mi
Time ZoneCentral Time Zone (CST/CDT)
Major HighwaysInterstate 57, Interstate 55 nearby region, U.S. Route 62, Missouri Route 80
Major RiversMississippi River, Ohio River nearby region
Neighboring CountiesScott County, New Madrid County, Ballard County (Kentucky), Alexander County (Illinois)
Famous ForMississippi River Delta farmland, agriculture, bird migration areas, and river history
Top AttractionsBig Oak Tree State Park, Mississippi River scenery, Dorena-Hickman Ferry nearby region, and wildlife refuges
Official WebsiteOfficial Website

About Mississippi County

Mississippi County is located in the southeastern Bootheel region of Missouri along the Mississippi River and was established in 1845. The county seat is Charleston, while the Sikeston area nearby serves as a major regional center. The county is known for fertile agricultural land, river history, wetlands, and wildlife migration habitats.

Cities and Towns in Mississippi County, Missouri

City/TownPopulation (Census 2020)Latitude & Longitude
Charleston (county seat)5,19336.9209°N, 89.3501°W
East Prairie2,92236.7792°N, 89.3859°W
Bertrand82136.8945°N, 89.4534°W
Diehlstadt16336.8203°N, 89.4073°W
Anniston22636.8261°N, 89.3272°W
Wyatt21936.8717°N, 89.2220°W

What are the Golf Courses in Mississippi County

Golf CourseLocationLatitude & Longitude
Charleston Country ClubCharleston36.9294°N, 89.3621°W
East Prairie Recreation Golf AreaEast Prairie36.7868°N, 89.3976°W
Bootheel Regional Golf Course nearby regionSikeston area36.8785°N, 89.5973°W

Major Roads and Highways in Mississippi County

Major highways connect Mississippi County with the Missouri Bootheel, Kentucky, Illinois, and the Mississippi River corridor.

  • Interstate 57 - major north-south interstate through southeastern Missouri
  • Interstate 55 nearby region - important transportation corridor across the Mississippi Valley
  • U.S. Route 62 - east-west highway linking Missouri and Kentucky
  • Missouri Route 80 - regional route serving Bootheel agricultural communities

What are Neighboring Counties of Mississippi County

  • Scott County (northwest)
  • New Madrid County (southwest)
  • Alexander County, Illinois (northeast)
  • Ballard County, Kentucky (east)

What Are the Top Attractions in Mississippi County

The county offers river scenery, wetlands, wildlife refuges, and outdoor recreation in the Bootheel region.

  • Big Oak Tree State Park - wetlands, ancient cypress trees, hiking, and birdwatching
  • Mississippi River Scenic Areas - fishing, boating, and river photography locations
  • Dorena-Hickman Ferry nearby region - historic river crossing between Missouri and Kentucky
  • Ten Mile Pond Conservation Area - wildlife observation and hunting recreation
  • Charleston Historic District - local heritage landmarks and community attractions
  • Bird Migration Viewing Areas - seasonal waterfowl and wildlife habitats
  • Bootheel Agricultural Landscapes - scenic farmland and Delta region views
  • Fishing and Recreation Lakes - outdoor activities and family recreation
  • Community Festivals and Agricultural Events - local traditions and entertainment
  • Nature Trails and Wetland Viewing Platforms - environmental education and photography

What Is the Distance from Mississippi County to Nearby Cities

The following distances are measured by road (driving).

  • Charleston to Cape Girardeau (Cape Girardeau County), Missouri - 58 mi (93 km)
  • Charleston to Sikeston (Scott County), Missouri - 18 mi (29 km)
  • Charleston to Paducah (McCracken County), Kentucky - 49 mi (79 km)
  • Charleston to Cairo (Alexander County), Illinois - 25 mi (40 km)
  • Charleston to East Prairie (Mississippi County), Missouri - 10 mi (16 km)
  • Charleston to Bertrand (Mississippi County), Missouri - 7 mi (11 km)
  • Charleston to Memphis (Shelby County), Tennessee - 163 mi (262 km)
  • Charleston to St. Louis (St. Louis City), Missouri - 174 mi (280 km)
  • Charleston to Nashville (Davidson County), Tennessee - 196 mi (315 km)
  • Charleston to Little Rock (Pulaski County), Arkansas - 212 mi (341 km)
  • Charleston to Chicago (Cook County), Illinois - 382 mi (615 km)
  • Charleston to Kansas City (Jackson County), Missouri - 386 mi (621 km)
  • Charleston to Dallas (Dallas County), Texas - 522 mi (840 km)

FAQs about Mississippi County

Where is Mississippi County located?

Mississippi County is located in the southeastern Missouri Bootheel along the Mississippi River.

What is the population of Mississippi County?

Mississippi County had a population of 12,577 according to the 2020 United States Census.

What is Mississippi County known for?

Mississippi County is known for fertile farmland, wetlands, wildlife migration, and Mississippi River history.

What are the major highways in Mississippi County?

The county is served by Interstate 57, nearby Interstate 55, U.S. Route 62, and Missouri Route 80.

Are there golf courses in Mississippi County?

Yes, Mississippi County includes golf facilities such as Charleston Country Club and recreation golf areas near East Prairie.

References

  1. QuickFacts - U.S. Census Bureau
  2. United States Census Bureau
  3. United States Geological Survey (USGS)
  4. National Geodetic Survey
  5. Official Website